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1

Cardiac repair in guinea pigs with human engineered heart tissue from induced pluripotent stem cells

Weinberger, F., Breckwoldt, K., Pecha, S., Kelly, A., Geertz, B., Starbatty, J., Yorgan, T., Cheng, K.-H., Lessmann, K., Stolen, T., Scherrer-Crosbie, M., Smith, G., Reichenspurner, H., Hansen, A., Es

Journal:

Science Translational Medicine

Year:

2016

Language:

english

File:

PDF, 25.72 MB

english, 2016

2

The Formation of Calcified Nanospherites during Micropetrosis Represents a Unique Mineralization Mechanism in Aged Human Bone

Milovanovic, Petar, Zimmermann, Elizabeth A., vom Scheidt, Annika, Hoffmann, Björn, Sarau, George, Yorgan, Timur, Schweizer, Michaela, Amling, Michael, Christiansen, Silke, Busse, Björn

Journal:

Year:

2016

Language:

english

File:

PDF, 3.39 MB

english, 2016

3

Wnt1 is an Lrp5-independent bone-anabolic Wnt ligand

Luther, Julia, Yorgan, Timur Alexander, Rolvien, Tim, Ulsamer, Lorenz, Koehne, Till, Liao, Nannan, Keller, Daniela, Vollersen, Nele, Teufel, Stefan, Neven, Mona, Peters, Stephanie, Schweizer, Michaela

Journal:

Science Translational Medicine

Year:

2018

Language:

english

File:

PDF, 8.72 MB

english, 2018

4

Effects of Extracellular Phosphate on Gene Expression in Murine Osteoblasts

Rendenbach, C., Yorgan, T. A., Heckt, T., Otto, B., Baldauf, C., Jeschke, A., Streichert, T., David, J. P., Amling, M., Schinke, T.

Journal:

Calcified Tissue International

Year:

2014

Language:

english

File:

PDF, 445 KB

english, 2014

5

Increased Col10a1 expression is not causative for the phenotype of Phex-deficient Hyp mice

Yorgan, Timur, Rendenbach, Carsten, Jeschke, Anke, Amling, Michael, Cheah, Kathryn S.E., Schinke, Thorsten

Journal:

Biochemical and Biophysical Research Communications

Year:

2013

Language:

english

File:

PDF, 2.18 MB

english, 2013

6

Hepatic lipase is expressed by osteoblasts and modulates bone remodeling in obesity

Bartelt, Alexander, Beil, F. Timo, Müller, Brigitte, Koehne, Till, Yorgan, Timur A., Heine, Markus, Yilmaz, Tayfun, Rüther, Wolfgang, Heeren, Joerg, Schinke, Thorsten, Niemeier, Andreas

Journal:

Year:

2014

Language:

english

File:

PDF, 1.07 MB

english, 2014

7

Structure–Activity Relationship of Adenosine 5′-diphosphoribose at the Transient Receptor Potential Melastatin 2 (TRPM2) Channel: Rational Design of Antagonists

Moreau, Christelle, Kirchberger, Tanja, Swarbrick, Joanna M., Bartlett, Stephen J., Fliegert, Ralf, Yorgan, Timur, Bauche, Andreas, Harneit, Angelika, Guse, Andreas H., Potter, Barry V. L.

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 4.75 MB

english, 2013

8

Relevance of Wnt signaling for osteoanabolic therapy

Timur A Yorgan,Thorsten Schinke

Journal:

Molecular and Cellular Therapies

Year:

2014

Language:

english

File:

PDF, 668 KB

english, 2014

9

The Anti-Osteoanabolic Function of Sclerostin Is Blunted in Mice Carrying a High Bone Mass Mutation of Lrp5

Yorgan, Timur A, Peters, Stephanie, Jeschke, Anke, Benisch, Peggy, Jakob, Franz, Amling, Michael, Schinke, Thorsten

Journal:

Journal of Bone and Mineral Research

Year:

2015

Language:

english

File:

PDF, 1.73 MB

english, 2015

10

Immediate effects of retinoic acid on gene expression in primary murine osteoblasts

Yorgan, Timur A., Heckt, Timo, Rendenbach, Carsten, Helmis, Christina, Seitz, Sebastian, Streichert, Thomas, Amling, Michael, Schinke, Thorsten

Journal:

Journal of Bone and Mineral Metabolism

Year:

2016

Language:

english

File:

PDF, 994 KB

english, 2016

11

Lincoln Junior High Administers an Accelerated Progra m for Superior Students

Journal:

Year:

1960

Language:

english

File:

PDF, 337 KB

english, 1960

12

I Can Read

Journal:

Year:

1958

Language:

english

File:

PDF, 852 KB

english, 1958

13

Impaired bone remodeling and its correction by combination therapy in a mouse model of mucopolysaccharidosis-I

S. C. Kuehn, T. Koehne, K. Cornils, S. Markmann, C. Riedel, J. M. Pestka, M. Schweizer, C. Baldauf, T. A. Yorgan, M. Krause, J. Keller, M. Neven, S. Breyer, R. Stuecker, N. Muschol, B. Busse, T. Braul

Year:

2015

Language:

english

File:

PDF, 1.41 MB

english, 2015

14

Osteoblast-specific Notch2 inactivation causes increased trabecular bone mass at specific sites of the appendicular skeleton

Yorgan, Timur, Vollersen, Nele, Riedel, Christoph, Jeschke, Anke, Peters, Stephanie, Busse, Bjoern, Amling, Michael, Schinke, Thorsten

Journal:

Year:

2016

Language:

english

File:

PDF, 788 KB

english, 2016

15

Hypochlorhydria-induced calcium malabsorption does not affect fracture healing but increases post-traumatic bone loss in the intact skeleton

Haffner-Luntzer, Melanie, Heilmann, Aline, Heidler, Verena, Liedert, Astrid, Schinke, Thorsten, Amling, Michael, Yorgan, Timur Alexander, vom Scheidt, Annika, Ignatius, Anita

Journal:

Journal of Orthopaedic Research

Year:

2016

Language:

english

File:

PDF, 2.46 MB

english, 2016

16

A rare schizophrenia risk variant of CACNA1I disrupts CaV3.3 channel activity

Andrade, A., Hope, J., Allen, A., Yorgan, V., Lipscombe, D., Pan, J. Q.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.82 MB

english, 2016

17

The Lrp4 R1170Q homozygous knock-in mouse recapitulates the bone phenotype of sclerosteosis in humans

Boudin, Eveline, Yorgan, Timur, Fijalkowski, Igor, Sonntag, Stephan, Steenackers, Ellen, Hendrickx, Gretl, Peeters, Silke, Maré, Annelies De, Vervaet, Benjamin, Verhulst, Anja, Mortier, Geert, D'Haese

Journal:

Journal of Bone and Mineral Research

Year:

2017

Language:

english

File:

PDF, 1.42 MB

english, 2017

18

Vitamin D regulates osteocyte survival and perilacunar remodeling in human and murine bone

Rolvien, Tim, Krause, Matthias, Jeschke, Anke, Yorgan, Timur, Püschel, Klaus, Schinke, Thorsten, Busse, Björn, Demay, Marie B., Amling, Michael

Journal:

Year:

2017

Language:

english

File:

PDF, 1.78 MB

english, 2017

19

Severe bone loss and multiple fractures in SCN8A -related epileptic encephalopathy

Rolvien, Tim, Butscheidt, Sebastian, Jeschke, Anke, Neu, Axel, Denecke, Jonas, Kubisch, Christian, Meisler, Miriam H., Pueschel, Klaus, Barvencik, Florian, Yorgan, Timur, Oheim, Ralf, Schinke, Thorste

Journal:

Year:

2017

Language:

english

File:

PDF, 1016 KB

english, 2017

20

High bone turnover in mice carrying a pathogenic Notch2-mutation causing Hajdu-Cheney syndrome

Vollersen, Nele, Hermans-Borgmeyer, Irm, Cornils, Kerstin, Fehse, Boris, Rolvien, Tim, Triviai, Ioanna, Jeschke, Anke, Oheim, Ralf, Amling, Michael, Schinke, Thorsten, Yorgan, Timur Alexander

Journal:

Journal of Bone and Mineral Research

Year:

2017

Language:

english

File:

PDF, 2.20 MB

english, 2017

21

The high bone mass phenotype of Lrp5 -mutant mice is not affected by megakaryocyte depletion

Yorgan, Timur, David, Jean-Pierre, Amling, Michael, Schinke, Thorsten

Journal:

Biochemical and Biophysical Research Communications

Year:

2018

Language:

english

File:

PDF, 2.72 MB

english, 2018

22

Lysosomal proteome and secretome analysis identifies missorted enzymes and their non-degraded substrates in mucolipidosis III mouse cells

Di Lorenzo, Giorgia, Voltolini Velho, Renata, Winter, Dominic, Thelen, Melanie, Ahmadi, Shiva, Schweizer, Michaela, De Pace, Raffaella, Cornils, Kerstin, Yorgan, Timur Alexander, Grüb, Saskia, Hermans

Journal:

Molecular & Cellular Proteomics

Year:

2018

File:

PDF, 1.59 MB

2018

23

Differential effects of Calca-derived peptides in male mice with diet-induced obesity

Bartelt, Alexander, Jeschke, Anke, Müller, Brigitte, Gaziano, Isabella, Morales, Michelle, Yorgan, Timur, Heckt, Timo, Heine, Markus, Gagel, Robert F., Emeson, Ronald B., Amling, Michael, Niemeier, An

Journal:

Year:

2017

Language:

english

File:

PDF, 11.29 MB

english, 2017

24

Post-weaning epiphysiolysis causes distal femur dysplasia and foreshortened hindlimbs in fetuin-A-deficient mice

Brylka, Laura J., Köppert, Sina, Babler, Anne, Kratz, Beate, Denecke, Bernd, Yorgan, Timur A., Etich, Julia, Costa, Ivan G., Brachvogel, Bent, Boor, Peter, Schinke, Thorsten, Jahnen-Dechent, Willi, Mi

Journal:

Year:

2017

Language:

english

File:

PDF, 26.69 MB

english, 2017

25

Conditional mouse models support the role of SLC39A14 (ZIP14) in Hyperostosis Cranialis Interna and in bone homeostasis

Hendrickx, Gretl, Borra, Vere M., Steenackers, Ellen, Yorgan, Timur A., Hermans, Christophe, Boudin, Eveline, Waterval, Jérôme J., Jansen, Ineke D. C., Aydemir, Tolunay Beker, Kamerling, Niels, Behets

Journal:

Year:

2018

Language:

english

File:

PDF, 19.28 MB

english, 2018

26

Human iPS cell-derived engineered heart tissue does not affect ventricular arrhythmias in a guinea pig cryo-injury model

Pecha, Simon, Yorgan, Kaja, Röhl, Matti, Geertz, Birgit, Hansen, Arne, Weinberger, Florian, Sehner, Susanne, Ehmke, Heimo, Reichenspurner, Hermann, Eschenhagen, Thomas, Schwoerer, Alexander Peter

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 1.37 MB

english, 2019

27

Human iPS cell-derived engineered heart tissue does not affect ventricular arrhythmias in a guinea pig cryo-injury model

Pecha, Simon, Yorgan, Kaja, Röhl, Matti, Geertz, Birgit, Hansen, Arne, Weinberger, Florian, Sehner, Susanne, Ehmke, Heimo, Reichenspurner, Hermann, Eschenhagen, Thomas, Schwoerer, Alexander Peter

Journal:

Scientific Reports

Year:

2019

File:

PDF, 1.37 MB

2019

28

Mice lacking plastin-3 display a specific defect of cortical bone acquisition

Yorgan, Timur Alexander, Sari, Hatice, Rolvien, Tim, Windhorst, Sabine, Failla, Antonio Virgilio, Kornak, Uwe, Oheim, Ralf, Amling, Michael, Schinke, Thorsten

Journal:

Year:

2020

File:

PDF, 3.85 MB

2020

29

Mice carrying a ubiquitous R235W mutation of Wnt1 display a boneâspecific phenotype

Yorgan, Timur Alexander, Rolvien, Tim, StÃ¼rznickel, Julian, Vollersen, Nele, Lange, Fabiola, Zhao, Wenbo, Baranowsky, Anke, Rosenthal, Lana, HermansâBorgmeyer, Irm, Sharaf, Ahmed, Karsak, Meliha, D

Journal:

Journal of Bone and Mineral Research

Year:

2020

File:

PDF, 5.47 MB

2020

30

Gnathodiaphyseal dysplasia is not recapitulated in a respective mouse model carrying a mutation of the Ano5 gene

Rolvien, Tim, Avci, Osman, von Kroge, Simon, Koehne, Till, Selbert, Stefan, Sonntag, Stephan, Shmerling, Doron, Kornak, Uwe, Oheim, Ralf, Amling, Michael, Schinke, Thorsten, Yorgan, Timur Alexander

Journal:

Year:

2020

File:

PDF, 2.15 MB

2020

31

The neuropeptide calcitonin gene-related peptide alpha is essential for bone healing

Appelt, Jessika, Baranowsky, Anke, Jahn, Denise, Yorgan, Timur, KÃ¶hli, Paul, Otto, Ellen, Farahani, Saeed Khomeijani, Graef, Frank, Fuchs, Melanie, Herrera, AarÃ³n, Amling, Michael, Schinke, Thorsten

Journal:

Year:

2020

File:

PDF, 4.72 MB

2020

32

Imbalanced cellular metabolism compromises cartilage homeostasis and joint function in a mouse model of mucolipidosis type III gamma

Westermann, Lena M., Fleischhauer, Lutz, Vogel, Jonas, Jenei-Lanzl, Zsuzsa, Floriano Ludwig, Nataniel, Schau, Lynn, Morellini, Fabio, Baranowsky, Anke, Yorgan, Timur A., Di Lorenzo, Giorgia, Schweizer

Journal:

Disease Models & Mechanisms

Year:

2020

File:

PDF, 2.43 MB

2020

33

Piezo1 Inactivation in Chondrocytes Impairs Trabecular Bone Formation

Hendrickx, Gretl, Fischer, Verena, Liedert, Astrid, von Kroge, Simon, HaffnerâLuntzer, Melanie, Brylka, Laura, Pawlus, Eva, Schweizer, Michaela, Yorgan, Timur, Baranowsky, Anke, Rolvien, Tim, Neven,

Journal:

Journal of Bone and Mineral Research

Year:

2020

File:

PDF, 3.10 MB

2020

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